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Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. Semaphorin 4D (Sema4D) also known as CD100, is a widely expressed 150 kDa type I transmembrane glycoprotein of the Class 4 Semaphorin family with activity in the immune and nervous systems. free DNS zone file hosting. , you have two options: Run your own local DNS server, with a record for *.